Found 12 matching trials
Tolerability of Inhaled Hypertonic Saline in Infants With Cystic Fibrosis
NAThis is an open-label pilot study of the safety and tolerability of 7% hype...
Location
University of North Carolina
Clearing Lungs With Epithelial Sodium Channel (ENaC) Inhibition in Cystic Fibrosis (CF)
PHASE2The goal of the study is to evaluate the safety and tolerability of P-1037 ...
Location
Children's Hospital of Los Angeles
Impact of Discontinuing Hypertonic Saline in People With CF on Highly Effective CFTR Modulators- A SIMPLIFY Sub-Study
NADespite the increasingly common use of cystic fibrosis transmembrane conduc...
Location
University of Alabama at Birmingham
Clearing Lungs With ENaC Inhibition in Primary Ciliary Dyskinesia
PHASE2To evaluate the safety and efficacy of treatment with VX-371 with and witho...
Location
Multiple Locations
A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation
PHASE2The purpose of this study is to evaluate the safety and efficacy of treatme...
Location
Multiple Locations
Saline Hypertonic in Preschoolers + CT
PHASE2The purpose of this study is to assess whether inhalation of 7% hypertonic ...
Location
Children's Hospital of Colorado
Is a Single Daily Session Combining HS + Physio Sufficient to Obtain Long-term Clinical Benefits in Bronchiectasis?
NAThe present study will aim to find out whether a home treatment in people w...
Rethinking Early Airway Clearence Therapies
NAThe REACT trial consists of two parallel, randomized studies; the Hypertoni...
Location
The Children's Hospital Alabama, University of Alabama at Birmingham
Hypertonic Saline in NCFB
PHASE4The purpose of this single arm clinical trial is to evaluate the effects of...
Location
University of North Carolina at Chapel Hill
Preventive Inhalation of Hypertonic Saline in Infants With Cystic Fibrosis
PHASE2The purpose of this study is to assess whether 6% hypertonic saline (HS) is...
Location
University Children's Hospital Heidelberg, Cystic Fibrosis Centre